Daily sentiment
Net daily sentiment ranged from -28.55 for on Monday the 19th to 19.28 for on Thursday the 22nd.
The sentiment for each tweet is scored from -1 (most negative) to +1 (most positive) using VADER sentiment analysis. Net sentiment is calculated by summing the sentiment across all tweets for a given day and/or category, then normalizing the score by the number of tweets.
Medical conditions from the MedDRA dictionary
Anxiety was the most frequently observed medical condition mentioned. Insomnia had the highest overall net sentiment of 8.48. Crying had the lowest net sentiment this week (-39.56).
| medical condition | count | sentiment |
|---|---|---|
| Anxiety | 83 | -3.40 |
| Pain | 59 | -8.69 |
| ADHD | 22 | 2.83 |
| Coldness, Cold | 19 | -13.20 |
| Insomnia | 18 | 8.48 |
| Crying | 17 | -39.56 |
| Sickness | 15 | -12.91 |
| Forgetfulness | 14 | -10.89 |
| Sweating | 12 | 3.84 |
| Fall | 11 | 8.11 |
MedDra is a standardized medical terminology developed by the International Council for Harmonization Cross-referencing tweets against this list is a starting point for identifying medical conditions mentioned in tweets.
Cross-referencing the MedDRA dictionary by sentiment and topic
Positive tweets:
There were 120 tweets with an strong positive sentiment. The top 10 most frequent medical conditions mentioned within these tweets were (1) Anxiety, (2) Pain, (3) ADHD, (4) Sleepiness, Sleepy, (5) Insomnia, (6) Sweating, (7) Forgetfulness, (8) Addiction, (9) Fall, (10) Migraine. Of these terms, Sleepiness, Sleepy (n=7), Addiction (n=3), Migraine (n=3) were not in the top 10 most frequent terms across all tweets.
Negative tweets:
There were 144 tweets with an strong negative sentiment. The top 10 most frequent medical conditions mentioned within these tweets were (1) Anxiety, (2) Pain, (3) Crying, (4) Numbness, (5) Coldness, Cold, (6) Forgetfulness, (7) ADHD, (8) Fall, (9) Sickness, (10) Sweating. Of these terms, Numbness (n=8) were not in the top 10 most frequent terms across all tweets.
Word-level analysis
The 25 most important words within positive tweets (compared to negative and neutral) tweets are shown in the treemap below. The size of each box represents the weighted score of each word. The word “fluorid” within the search for “Fluoxetine” had the highest overall weight. When the words are summed for each topic, Sertraline had the highest overall weight.
The 25 most important words within negative tweets (compared to positive and neutral) tweets are shown in the treemap below. The word “veget” within the search for “Tryptophan” had the highest overall weight. When the words are summed for each topic, “Sertraline” had the highest overall weight within negative tweets.
This analysis of words evaluates the stemmed version of words using the Snowball algorithm. By stemming words, words with similar meaning, such as pain, painful & pained, are grouped together as simply “pain”.
Beta: text classification
Tweets that describe adverse events/side effects (first person point of view)
| tweet | search topic(s) | medical condition(s) mentioned |
|---|---|---|
| idk about Zoloft but Fluoxetine made me want to off myself fr on the first day and gave me the worst stomach ache of all time | fluoxetine | Ache, Stomach ache |
| Doing both 9th and 10th update today because I forgot <U+0001FAE3> 9th day: I was actually feeling pretty great, some minor pain from my first day on Loestrin Fe but all in all, yesterday was a good day. #anxiety #fluoxetine #loestrinfe | fluoxetine | Anxiety, Pain |
| _HD I was given amitriptyline for my nerve pain in upper legs. Supposed to take 30 mins before bedtime. Have to say its one bonus , I fell asleep really quickly, and slept like a log. Did take a bit longer in mornings to get going. Downside was I felt it made me feel more confused. | amitriptyline | Confused, Confusion, Nerve pain, Pain |
| my dreams on sertraline? weird as shit. my dreams when i forget to take my sertraline? the weirdest fuckin most vivid dreams you could ever imagine | sertraline | Forgetfulness, Vivid dreams |
| Hi I had an mri and ct scan both with contrast dye, I have the same pains, but worse today left side of head down side of ear and neck, also pain in lower right hip, doctor will not give me painkillers only amitriptyline 10mg, not doing anything, I have been laid up all day, | amitriptyline | Pain |
| I sleep better on amitriptyline and it also helps my pain. Sleep still isn’t refreshing sleep, but better than waking up every 3 hours. So, between less fatigue from pain and a better sleep, I have more energy than with more pain/worse sleep. | amitriptyline | Fatigue, Pain |
| A night back in late July/early august I took 1 gram of Sertraline. A few hours later and I vomited 5 times, my throat hurt afterwards | sertraline | Vomiting |
| Sertraline withdrawal dreams nightmares have begun. Can’t even describe the dream I just woke up from now but it was horrendous and I can’t believe my kind even came up with that Gonna try to sleep again…it’s gonna be a long night… | sertraline | Nightmare, Nightmares |
| I got prescribed trazodone and I forgot that I’m supposed to take it at bedtime cause this shit made me so sleepy | trazodone | Sleepiness, Sleepy |
| Lorazepam short term, and Citalopram long-term had been a game changer for me. I started the Citalopram low and slow, but by the time I got to half a tablet, I was not feeling any anxiety or depression. | citalopram | Anxiety |
| First day on Sertraline. Exhausted, nauseous and have a banger of a headache. Didn’t expect the side effects to start quite this quickly <U+0001F633><U+0001F615> | sertraline | Exhaustion, Headache, Nauseous |
| i eat like a handful every night just to get moderately sleepy i need my trazodone bsck | trazodone | Sleepiness, Sleepy |
| I ran out of trazodone and didn’t fall asleep until 6 this morning. I’m feeling so confused today. Everything feels out of place | trazodone | Confused, Confusion, Fall |
| im talking to my doctors next week, but i’ve been on sertraline for 5 weeks now and i am having fucking CONSTANT diarrhoea i dont think thats a good thing. | sertraline | Diarrhoea |
| I couldn’t get on with amitriptyline. I use that as an absolute last resort when it’s too bad but it knocks me out so much the next day I feel like I’ve got a massive hangover. I have two slipped discs too, had surgery on them but it failed. I feel your pain! X | amitriptyline | Hangover, Pain |
| to expand on this (mentions of SH and sewerslidal thoughts) I had started citalopram for my depression and anxiety— it really only helped my anxiety and made my depression worse. i SH and had to go on a 24 hour watch with my gf | citalopram | Anxiety |
| I had a doctor try to do that. Mydayis in the morning, trazodone at night. I’m sure it’s not the same thing, but without the trazodone, I might only get an hour of sleep a night. I stopped the ADHD meds after that. | trazodone | ADHD |
| i knew sweating was one of the side effects of sertraline but i didn’t think it’d be this excessive, i move a muscle and i’m sweating buckets | sertraline | Sweating |
| I keep getting these constant headaches. <U+0001F614> is it a side effect from the sertraline or am I just over cautious? | sertraline | Headache |
| took my trazodone and i can’t sleep all i have is a headache smh | trazodone | Headache |
This classifier was trained on a set of tweets manually reviewed and tagged. The classifier was trained using GloVe, a pretrained word embedding layer.
References
Webpage created in R version 4.1.0 (2021-05-18) and R Studio (Version 1.4.1717) using the following packages: plotly, kableExtra, formattable, treemap, and wordpressr.
- C. Sievert. Interactive Web-Based Data Visualization with R, plotly, and shiny. Chapman and Hall/CRC Florida, 2020.
- Hao Zhu (2021). kableExtra: Construct Complex Table with ‘kable’ and Pipe Syntax. R package version 1.3.4.
- Kun Ren and Kenton Russell (2021). formattable: Create ‘Formattable’ Data Structures. R package version 0.2.1.
- Martijn Tennekes (2021). treemap: Treemap Visualization. R package version 2.4-3.
- Simit Patel (2021). wordpressr: An API Wrapper for WordPress Site APIs. R package version 0.1.0.
- Hutto, C.J. & Gilbert, E.E. (2014). VADER: A Parsimonious Rule-based Model for Sentiment Analysis of Social Media Text. Eighth International Conference on Weblogs and Social Media (ICWSM-14). Ann Arbor, MI, June 2014.