Covid-19 Vaccines & Therapeutics Twitter Surveillance for the Week of Mar 13, 2022

DrugVisual Covid-19 Twitter Dashboard

Covid-19 in the news this week

  • Moderna seeks approval for a 2nd COVID-19 booster shot for adults
  • A surge in COVID-19 spurs new lockdowns in China’s cities
Worldwide Covid-19 new cases & deaths

worldwide Covid-19 new cases and deaths week of 2022-03-13


Daily sentiment

Net daily sentiment ranged from -37.79 for Remdesivir on Saturday the 19th to 20.23 for Johnson and johnson vaccine on Friday the 18th.

The sentiment for each tweet is scored from -1 (most negative) to +1 (most positive) using VADER sentiment analysis. Net sentiment is calculated by summing the sentiment across all tweets for a given day and/or category, then normalizing the score by the number of tweets.

daily sentiment for tweets discussin Covid-19 vaccines and therapeutics published between 2022-03-13 and 2022-03-19


Medical conditions from the MedDRA dictionary

Infection was the most frequently observed medical condition mentioned. Infection had the highest overall net sentiment of -4.5. Fear had the lowest net sentiment this week (-46.76).

medical condition count sentiment
Infection 256 -4.50
Cancer 77 -37.64
Sickness 73 -27.49
Flu 42 -39.54
Tinnitus 38 -35.73
Fear 34 -46.76
Migraine 34 -38.92
Poisoning 31 -24.95
Blindness, Blind 30 -12.06
Worry 30 -29.52

MedDra is a standardized medical terminology developed by the International Council for Harmonization Cross-referencing tweets against this list is a starting point for identifying medical conditions mentioned in tweets.


Cross-referencing the MedDRA dictionary by sentiment and topic

Positive tweets: There were 205 tweets with an strong positive sentiment. The top 10 most frequent medical conditions mentioned within these tweets were (1) Infection, (2) Sickness, (3) Blindness, Blind, (4) Cancer, (5) Flu, (6) MS, (7) Poisoning, (8) Fever, (9) Forgetfulness, (10) Coughing, Cough. Of these terms, MS (n=7), Fever (n=6), Forgetfulness (n=6), Coughing, Cough (n=4) were not in the top 10 most frequent terms across all tweets.

Meddra conditions associated with positive tweets about Covid-19 vaccines and therapeutics published between 2022-03-13 and 2022-03-19

Negative tweets: There were 516 tweets with an strong negative sentiment. The top 10 most frequent medical conditions mentioned within these tweets were (1) Infection, (2) Cancer, (3) Sickness, (4) Tinnitus, (5) Migraine, (6) Fear, (7) Flu, (8) Coughing, Cough, (9) Worry, (10) Poisoning. Of these terms, Coughing, Cough (n=18) were not in the top 10 most frequent terms across all tweets.

Meddra conditions associated with negative tweets about Covid-19 vaccines and therapeutics published between 2022-03-13 and 2022-03-19


Word-level analysis

The 25 most important words within positive tweets (compared to negative and neutral) tweets are shown in the treemap below. The size of each box represents the weighted score of each word. The word “got” within the search for “Ivermectin” had the highest overall weight. When the words are summed for each topic, Ivermectin had the highest overall weight.

words associated with positive tweets about Covid-19 vaccines and therapeutics published between 2022-03-13 and 2022-03-19

The 25 most important words within negative tweets (compared to positive and neutral) tweets are shown in the treemap below. The word “advers” within the search for “Pfizer vaccine” had the highest overall weight. When the words are summed for each topic, “Pfizer vaccine” had the highest overall weight within negative tweets.

words associated with negative tweets about Covid-19 vaccines and therapeutics published between 2022-03-13 and 2022-03-19

This analysis of words evaluates the stemmed version of words using the Snowball algorithm. By stemming words, words with similar meaning, such as pain, painful & pained, are grouped together as simply “pain”.


Beta: text classification

Tweets that describe adverse events/side effects (first person point of view)

tweet search topic(s) medical condition(s) mentioned
In the months immediately following covid I had random fever spikes, icepick headaches, chest pain, palpitations, cough and fatigue. The pfizer vaccine thankfully erased those almost completely. I do still occasionally have days I feel like a bus hit me. I’m grateful to be 95%. pfizer vaccine Chest pain, Coughing, Cough, Fatigue, Fever, Headache, Pain, Palpitations
I had a blood clot in my brain after taking the 2nd Pfizer vaccine. I never had such pain in my head before, it makes you think you need to go to the hospital. I am still having painful headaches like something is wrong, but it’s not as bad as before. I’m devastated. Fk Pfizer! pfizer vaccine Headache, Pain
I haven’t had COVID-19 but two days after my first Pfizer vaccine I developed severe inflammatory symptoms. Confusion, disoriented, fever, brain hurts, eyes hurt etc. got worse after 2nd shot. I have to take 8 antihistamines a day just to be able to sit on the couch all day. pfizer vaccine Confused, Confusion, Fever
I don’t feel major side-effects from the second Covid-19 Pfizer vaccine. All I felt was nausea for a few minutes the following day, but I did not throw up. pfizer vaccine Nausea
My puppins had his boosters yesterday. Parvovirus, distemper, and rabies. He was so sick after. Having Pfizer vaccine, I get ickiness/body hurts feels like. Had to go back to the vet for meds to make him feel better. never want my baby not feeling good. Love your babies! <U+2764><U+FE0F><U+2764><U+FE0F><U+2764><U+FE0F> pfizer vaccine Sickness
I had a hyper response to original C19–kicked most of it out in five days, but I was extra exhausted until I got the Moderna vaccine. So I totally get this. moderna vaccine Exhaustion
I’ve had asthma all my life. Ever since I can remember. I wake up every night gasping for air And need for my inhaler. Within about two weeks after taking the Pfizer vaccine my asthma completely went away. I no longer need my inhaler. I am glad this vaccine came out!!! pfizer vaccine Asthma, Gasping
After my 4th #moderna vaccine, I finally got side effects – chills, fever, headache, and injection site pain. For the first three shots, nothing. It started about four hours after the shot and all night – but I’m fine this morning. At least now I know my immune system is working! moderna vaccine Chills, Fever, Headache, Injection site pain, Pain
I’ve had serious heart palpitations since I took the second Moderna vaccine. moderna vaccine Palpitations
I took one shot of the J&amp;J vaccine plus three shots of the Moderna mRNA.

<U+0001F489>+<U+0001F489><U+0001F489>+<U+0001F489>

So my experience has been nothing more than that of catching a cold. Sneezing, drinking tea, chicken soup, citrus fruits, bundling up and watching Netflix. No fever, no ache. No loss of smell.

johnson and johnson vaccine Ache, Coldness, Cold, Fever, Loss of smell, Sneezing
I also had long covid symptoms, pretty severe at times…racing elevated heart rate, palpitations, fatigue, headaches. I took ivermectin and NAC. After 2nd day on ivermectin, my heart symptoms stopped and I have continued to get better. Also plantbased diets/green smoothies…1/2 ivermectin Fatigue, Headache, Palpitations
Pfizer vaccine, had severe chills, fever (101), dry heaves, 12 hours after receiving injection. Lasted for 6 miserable hours. Better than getting covid pfizer vaccine Chills, Dry heaves, Fever
I’m unvaccinated and recently got covid. Had a bit of a scratchy throat and some night sweats and was tired for about 10 days. I’m so glad I took #Ivermectin as it could have been so much worse without it. ivermectin Night sweats, Sweating
After getting the Moderna vaccine, I began 2 get pain N both hands, fingers locking &amp; numbness a few times. I have arthritis; but this has never happened before. I hope the vaccine wears off &amp; this pain goes away. It never happened before. Wish I hadn’t taken the damned shots. moderna vaccine Arthritis, Numbness, Pain
_tx I also had a severe reaction 5 days after receiving the Moderna vaccine. Severe joint and muscle pain, numbness in hands. I could barely walk.Blood tests show abnormal inflammatory markers.8 months later, pain is still severe. I wish that I’d never take the vaccine.<U+0001F623> moderna vaccine Muscle pain, Numbness, Numbness in hand, Pain
So I’ve been breaking out randomly in hives and my lip randomly gets swollen after getting my first dose of the moderna vaccine…. moderna vaccine Hives
Dose and I’ve only ever heard people have mild side effects. Sore arm, fatigue, headache, body aches lasting less than a day. My brother (in his 30’s) got myocarditis from the Pfizer vaccine. It was unpleasant but he fully recovered. When he got covid this year it was mild. (2) pfizer vaccine Ache, Fatigue, Headache
I only got my first Pfizer vaccine and ended up with slight heart inflammation, nuerological issues, and post viral pots 8 months later. I think I’ll pass. pfizer vaccine Inflammation
I also had a fever with the second Moderna vaccine but with the third everything went smoothly. Stay strong, Evelyn <U+0001F4AA><U+0001F603> moderna vaccine Fever
My arthritis has been giving me extreme pain in my hands since taking the Moderna vaccine. moderna vaccine Arthritis, Pain

This classifier was trained on a set of tweets manually reviewed and tagged. The classifier was trained using GloVe, a pretrained word embedding layer.

References

Webpage created in R version 4.1.0 (2021-05-18) and R Studio (Version 1.4.1717) using the following packages: plotly, kableExtra, formattable, treemap, and wordpressr.

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  • Kun Ren and Kenton Russell (2021). formattable: Create ‘Formattable’ Data Structures. R package version 0.2.1.
  • Martijn Tennekes (2021). treemap: Treemap Visualization. R package version 2.4-3.
  • Simit Patel (2021). wordpressr: An API Wrapper for WordPress Site APIs. R package version 0.1.0.
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